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โ† Trials
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Choroidal and Retinal Features in PACD and POAG on OCT and OCTA

Recruitingn/aAges 18 Years - 90 YearsAllZhongshan Ophthalmic Center, Sun Yat-sen Universiโ€ฆ
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In plain words

What the trial is, and whether it could suit you

Glaucoma is a group of irreversible, progressive optic neuropathies that can lead to severe visual field defects and even blindness, affecting nearly 95 million people worldwide. Based on anterior chamber angle structure, glaucoma is classified into primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG). Although POAG is more common, PACG is more severe and more likely to cause blindness if not managed appropriately. Globally, PACG accounts for approximately 25% of all glaucoma cases but is responsible for roughly 50% of glaucoma-related blindness. Generally, the term "glaucoma" implies optic nerve damage; however, glaucomatous optic neuropathy may be absent in subacute and acute angle-closure glaucoma. Therefore, according to international consensus, primary angle-closure disease is categorized as PACD-encompassing primary angle-closure suspect (PACS), primary angl

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Control group: Healthy individuals with no history of ocular surgery, IOP \< 21 mmHg, and CDR \< 0.5 bilaterally without asymmetry * Observation group: Glaucoma specialist-confirmed diagnosis of POAG or PACD (per ISGEO staging: PACS/PAC/PACG) Exclusion Criteria: * History of retinal or macular disease (e.g., AMD, DR, RVO, ERM) * Non-glaucomatous optic neuropathy (e.g., MS, NMO) * Poor OCT/OCTA image quality * Refusal to sign informed consent
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What it tests

  • Not listed
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Where

1 site
Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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