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Acute Ocular Effects of Cigarette Smoking

Recruitingn/aAges 18 Years - 60 YearsAllIstanbul University
NCT07580040 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective study aims to evaluate the short-term effects of smoking on corneal tomographic and biometric measurements in healthy adults. After baseline examinations and measurements are taken in both smoking and non-smoking participants, the same measurements will be repeated after 10 minutes of external exposure, and within-group and between-group changes will be compared. The aim of the study is to determine whether acute smoking exposure leads to measurable immediate changes in corneal tomographic and biometric parameters.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy adults aged 18 to 60 years * Current smokers in the smoking group * Never-smokers in the control group * Willing and able to undergo ophthalmic examination and Pentacam AXL measurements Exclusion Criteria: * History of ocular surgery or ocular trauma * Presence of corneal disease, retinal disease, or ocular surface disorder * Clinically significant dry eye disease * Contact lens use within the last 2 weeks * Use of medications that may affect the ocular surface or pupillary dynamics, including anticholinergics or sympathomimetics * Systemic diseases such as diabetes mellitus or hypertension * Former smoking history in the control group * Use of electronic cigarettes or other tobacco products * Inability to cooperate adequately for accurate measurement
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What it tests

  • Cigarette Smoking Exposure
  • No Smoking Exposure
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Where

1 site
Istanbul University, Istanbul Faculty of Medicine
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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