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Comparison of Hemodynamic Responses During Anesthesia Induction Using Eleveld and Schnider

Recruitingn/aAges 18 Years - anyAllIstanbul University
NCT07586189 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This randomized prospective study aims to compare the effects of two target-controlled infusion models, the Schnider and Eleveld models, on anesthetic depth and hemodynamic responses during anesthesia induction in adult patients undergoing spinal surgery. Patients scheduled for spinal surgery will be randomized into either the Schnider or Eleveld group. Before induction, standard monitoring will be applied, including electrocardiography, peripheral oxygen saturation, invasive arterial blood pressure monitoring, heart rate monitoring, and bispectral index monitoring. Anesthesia induction will be performed with fentanyl 2 mcg/kg, rocuronium 0.6 mg/kg, and propofol administered by target-controlled infusion with an effect-site target concentration of 3 mcg/mL according to the allocated pharmacokinetic model. Hemodynamic parameters and bispectral index values will be recorded before induct

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients scheduled for elective spinal surgery under general anesthesia * Patients who will undergo surgery at the Neurosurgery Department of Istanbul University, Istanbul Faculty of Medicine * Patients aged 18 years or older * Patients who provide written informed consent to participate in the study Exclusion Criteria: * Patients with uncontrolled hypertension * Patients with uncontrolled diabetes mellitus * Patients younger than 18 years of age * Patients who do not provide informed consent to participate in the study
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What it tests

  • TCI Propofol Injection Models- Eleveld
  • TCI Propofol Injection Schnider
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Where

1 site
Istanbul University
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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