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The Value of Early Postoperative Colonoscopy in The Early Diagnosis of Anastomotic Leakage After Surgery for Low Colorectal Cancer

RecruitingNAAges 18 Years - 80 YearsAllNanchong Central Hospital
NCT07588386 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether early postoperative colonoscopy is valuable in the early diagnosis of anastomotic leakage after surgery for low colorectal cancer.The main questions it aims to answer are: 1. Will the median diagnosis time of AL in the intervention group (early colonoscopy group) be significantly shorter than that in the control group? 2. Can targeted treatment (such as endoscopic vacuum therapy (EVT)) be initiated earlier in the early colonoscopy group, thereby reducing the incidence of AL and the rate of unplanned re-laparotomy? Researchers will compare the median diagnosis time of AL in the intervention group (early colonoscopy group) with the control group to observe whether early postoperative colonoscopy can detect anastomotic leakage earlier. Participants will: Experimental group (early colonoscopy group): 1. Colonoscopy will be performed on

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age 18-80 years old. 2. Pathologically diagnosed as colorectal adenocarcinoma. 3. The distance between the lower edge of the tumor and the anal verge is ≤15cm. 4. Accept laparoscopic or open radical resection and complete primary colorectal or colosal anastomosis. 5. Voluntarily participate and sign the written informed consent. Exclusion Criteria: 1. Distant metastasis was confirmed by emergency operation, palliative operation or intraoperative metastasis (M1). 2. Unsatisfactory anastomosis or poor blood circulation were found during the operation, and reinforcement suture or preventive colostomy were performed during the operation. 3. There are serious contraindications for enteroscopy (such as acute myocardial infarction, severe cardiopulmonary insufficiency, blood coagulation dysfunction, etc.). 4. Pregnant or lactating women. 5. Previous history of colorectal surgery (except endoscopic polypectomy). 6. Unable to understand or cooperate with the research process.
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What it tests

  • electronic colonoscopy
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Where

1 site
Beijing Anzhen Hospital Nanchong Hospital Affiliated to Capital Medical University
Nanchong, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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