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POCD After Major Gynecologic Surgery

Recruitingn/aAges 18 Years - anyFemaleFatihhan Zeytun
NCT07589348 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational cohort study aims to determine the incidence of early postoperative cognitive dysfunction (POCD) in patients undergoing major gynecological surgery. Cognitive function will be assessed using the Montreal Cognitive Assessment (MoCA) preoperatively and on postoperative day 3. POCD will be defined as a ≥20% relative decline or ≥2-point decrease in MoCA score. The study will also evaluate the association between POCD and perioperative clinical, surgical, and inflammatory parameters.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female patients aged ≥18 years * Scheduled for elective major gynecological surgery under general anesthesia * Total abdominal hysterectomy and/or bilateral salpingo-oophorectomy * Open or laparoscopic surgical approach * Ability to complete the Turkish version of the Montreal Cognitive Assessment (MoCA) * Ability to understand and provide written informed consen Exclusion Criteria: * Pre-existing dementia or major neurocognitive disorder * History of cerebrovascular event within the previous 3 months * Severe visual or hearing impairment preventing cognitive assessment * Emergency or hemodynamically unstable surgery * Planned postoperative sedation or mechanical ventilation longer than 72 hours * Postoperative delirium detected during assessment * Inability to communicate or cooperate * Refusal to participate
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What it tests

  • Not listed
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Where

1 site
University of Health Sciences Kocaeli City Hospital
İzmit, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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