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โ† Trials
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OptiMAx Will Test Whether SQ-LNS Incentivises Vaccination Uptake in Rural Chad and Niger, With a Cost Effectiveness Analysis. It Will Also Look at Whether Having Received SQ-LNS Before Becoming Malnourished Leads to Better Outcomes for Children Treated Under the OptiMA Protocol.

RecruitingNAAges 6 Months - 59 MonthsAllAlliance for International Medical Action
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In plain words

What the trial is, and whether it could suit you

Malnutrition and infectious disease form a vicious circle, posing a double threat to vulnerable children in low- and middle-income countries. Malnutrition makes children more vulnerable to infectious diseases, while infectious diseases increase the risk of malnutrition. When caught in this cycle, children are far more likely to die or suffer adverse effects on their health and development. High rates of wasting and low immunization coverage also constitute a weakening double burden for already fragile health systems. Every year in these contexts, hundreds of thousands of children are treated for severe wasting, while at the same time suffering repeated and prolonged epidemics of vaccine-preventable diseases such as measles. Rural areas of Chad and Niger are at the heart of this dynamic, recording some of the worst indicators of malnutrition and low vaccination coverage rates. Small-quan

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * All non-malnourished children between 6 and 12 months of age will be eligible for SQ-LNS supplementation until they reach 18 months of age. For the annual household surveys, * Children aged 6 to 59 months will be surveyed on MUAC status and other malnutrition-related issues, while the immunization analysis will focus on children aged 12 to 23 months; * With the informed oral consent of the parents or legal guardian ; * Reside in the neighborhoods included in the study. For the mixed-methods process evaluation and gender sub-study (to be carried out in the months following implementation). Inclusion criteria * OptiMAx intervention personnel (e.g. healthcare staff) * A group of mothers of children benefiting from the intervention * Male partners/spouses of parents * Community members from the sites targeted by the intervention will be recruited for the focus groups. * Non-adherents or parents who choose not to continue nutritional supplementation and/or vaccination despite their availability under the program will be recruited for interviews. * Husbands/male partners of non-members will also be surveyed. Exclusion Criteria: * Age-eligible children with MUAC \<125 or edema will first be treated for acute malnutrition with OptiMA and then resume supplementation with SQ-LNS. There is no exclusion criteria for the annual household surveys Exclusion criteria for the mixed-methods process evaluation \- Parents or guardians under 15 years of age.
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What it tests

  • small quantity lipid-based supplement (SQ-LNS)
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Where

2 sites
Ngouri hospital
Ngouri, Chad
Mirriah hospital
Mirriah, Niger
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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