Pathway to Peanut Tolerance

Inclusion Criteria: * Subject's parent and/ or guardian must be able to understand and provide informed consent. * Age 2 to 17 years of age * Either sex * Any race, any ethnicity * Have a history of sensitization \[positive skin prick test to peanut extract as defined by wheal size at least 3mm above control OR peanut-specific IgE ≥0.35 kUA/L\] Exclusion Criteria: Individuals who meet any of these criteria are not eligible for enrolment: * Any disorder in which adrenaline is contraindicated (such as hypertension or cardiac rhythm disorders) * History of chronic diseases requiring therapy (other than asthma, atopic dermatitis, allergic rhinitis) * Past or current major illness that in the opinion of the Site investigator may affect the subject's ability to participate in the study e.g. increased risk to the participant * Concurrent treatment with any allergen immunotherapy * Participation in any trials of therapeutic interventions for FA, or therapy with anti-IgE or other biologics within 1 year of enrolment * Current uncontrolled or moderate to severe asthma as defined by FEV1 value \<80% predicted for participants aged 7 years or older and are able to perform spirometry * Gastrointestinal eosinophilic disorders * Use of short-acting antihistamine (e.g. chlorpheniramine) within 3 days prior to open-labelled food challenge or skin testing, or medium-acting antihistamine (e.g. cetirizine, loratadine) within 5 days prior to open-labelled food challenge or skin testing * Use of beta-blockers, ACE inhibitors, angiotensin-receptor blockers or calcium channel blockers