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Hematological Indices and Sympathetic Block Response in Neuropathic Pain

Recruitingn/aAges 18 Years - anyAllAnkara City Hospital Bilkent
NCT07596823 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as part of routine clinical care. Hematological parameters including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), aggregate index of systemic inflammation (AISI), and red cell distribution width (RDW) will be evaluated before and after treatment. The association between changes in these indices and pain outcomes will be analyzed.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Diagnosis of neuropathic pain based on clinical evaluation * DN4 and/or LANSS scores compatible with neuropathic pain * Undergoing sympathetic nerve block as part of routine clinical treatment * Availability of pre-treatment and follow-up hemogram parameters * Ability to provide written informed consent Exclusion Criteria: * Age \<18 years * Active infection or acute inflammatory disease * Active malignancy * History of hematological disease * Immunosuppressive therapy or systemic corticosteroid use * Major surgery or severe trauma within the last month * Pregnancy or breastfeeding * Autoimmune or rheumatologic inflammatory disease * Missing follow-up data
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What it tests

  • Not listed
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Where

1 site
Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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