Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases

Inclusion Criteria: * Adult patient aged 18 years or older. * Diagnosis or documented clinical suspicion of chronic lung disease, including interstitial lung disease, pulmonary granulomatosis such as sarcoidosis, or pulmonary emphysema. * Availability of a lung tissue biopsy sample obtained during routine medical care and stored as a formalin-fixed paraffin-embedded sample. * Sufficient medical record information to document the clinical context, occupational or environmental exposure history, smoking status, imaging, pathology reports, and other relevant routine-care data. * No documented objection to the secondary use of health data and biological samples for this research. Exclusion Criteria: * Documented objection to participation in the study or to the secondary use of health data or biological samples for research. * Missing, unavailable, degraded, or technically unusable biopsy sample. * Insufficient medical record information to document the clinical context or exposure history. * Lung condition outside the scope of the study, such as isolated acute infection, isolated cardiac disease, or primary lung cancer. * Patient under legal protection when the applicable legal conditions for non-opposition cannot be fulfilled.