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โ† Trials
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Transcutaneous Auricular Vagus Nerve Stimulation Treatment for Rosacea

RecruitingNAAges 18 Years - anyAllBrigham and Women's Hospital
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In plain words

What the trial is, and whether it could suit you

A single arm, pilot study among individuals with rosacea and at least moderate flushing or rednesss will be enrolled in a 4-week trial of taVNS. The particicpants will be followed for an additional 4-weeks following the intervention period to evaluate the durability of the results

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years of age and older * Dermatologist confirmed diagnosis of rosacea * Clinician's Erythema Assessment of at least 3 (moderate to severe disease) * Willingness to adhere to current rosacea regimen without additions or laser treatments (e.g. PDL) during the study period. Exclusion Criteria: * Changes to rosacea regimen (prescription topical or oral medications) within 4 weeks of randomization. * Facial hair, tattoos, or other characteristics that would interfere with erythema assessments * History of symptomatic cardiac arrythmias (e.g. heart block, sick sinus syndrome, bradyarrhythmia) * Presence of a pacemaker, implanted defibrillator, or neurostimulator * Seizure disorder or epilepsy * Trigeminal Neuralgia within the past year * Severe coronary disease or recent myocardial infarction within the past 5 years * Severe autonomic dysfunction (e.g., frequent syncope, hospitalization) * History of recurrent syncope or unexplained fainting * Use of brimonidine or oxymetazoline within the past 4 weeks * Use of beta-blockers, anticholinergics, or vagal-modulating drugs within the past 4 weeks * Severe phymatous rosacea * Ear deformity, piercings, or other condition that prevents the use of the taVNS device * Known hypersensitivity to electrode materials * Patients who are pregnant.
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What it tests

  • Transaricular vagus nerve stimulation (taVNS)
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Where

1 site
Brigham and Women's Hospital
Boston, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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