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LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol B

Recruitingn/aAges 18 Years - anyAllMassachusetts General Hospital
NCT07600801 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This research is being done to determine if an image-based deep learning model (Sybil) can accurately predict the likelihood of future lung cancer based on chest computed tomography (CT) imaging from individuals with a family history of lung cancer.

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📋 Eligibility rules (as published)
Inclusion Criteria: * ≥18 years of age * Positive family history of lung cancer (defined as): * Has ≥1 first-degree relative OR * Has ≥2 second-degree relatives with a diagnosis of non-small cell lung cancer or small cell lung cancer (NB: a first-degree relative = parent, sibling, or child, a second-degree relative = grandparent, blood-related aunt or uncle, grandchild, blood-related niece or nephew, half-sibling) * Willing to provide images from at least one previously obtained CT Chest scan, if available. Exclusion Criteria: \- None
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What it tests

  • CT scan
  • Sybil
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Where

1 site
Massachusetts General Hospital
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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