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Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty

RecruitingNAAges 50 Years - 65 YearsAllLahore University of Biological and Applied Scien…
NCT07601906 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM), swelling, impaired proprioception, and kinesiophobia, which may delay functional recovery. Conventional physiotherapy is the standard rehabilitation approach following TKA; however, high-load strengthening exercises are often limited in the early postoperative phase due to pain and reduced tolerance. Blood flow restriction (BFR) exercise is an emerging rehabilitation technique that enables low-load exercise to produce strength adaptations similar to high-intensity training. While evidence supports its effectiveness for improving muscle strength, its effects on other outcomes such as pain, swelling, proprioception, and kinesiophobia are not well established. This ra

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients of age 50-65 years. 2. Primary unilateral TKA due to osteoarthritis. 3. Individuals with mild to moderate postoperative pain (NPRS score 4-7). 4. Minimum active knee flexion of 30° \& an extension lag of no more than 15°. 5. Patients should be medically stable, cognitively able to follow instructions in Urdu or english, and willing to provide written informed consent Exclusion Criteria: 1. History of deep vein thrombosis within the last six months. 2. Peripheral vascular disease and active infection. 3. Severe cardiovascular conditions 4. Neurological disorders affecting lower limb function
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What it tests

  • Blood Flow Restriction Exercises and Conventional Physical Therapy
  • Conventional Physical Therapy alone
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Where

1 site
Saleem Memorial Trust Hospital
Lahore, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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