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Observational Study of Electrical Impedance Tomography for Non-Invasive Assessment of Cerebral Autoregulation in Neurocritical Patients

Recruitingn/aAges 18 Years - anyAllXijing Hospital
NCT07602114 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a single-center, prospective, observational, self-controlled clinical study conducted at the Neurosurgical Intensive Care Unit of Xijing Hospital, The First Affiliated Hospital of Air Force Military Medical University. The study aims to evaluate whether non-invasive Electrical Impedance Tomography (EIT) can reliably assess cerebral blood flow autoregulation in neurocritically ill participants, by comparing EIT-derived parameters with the current gold-standard invasive index PRx. Cerebral blood flow autoregulation helps maintain stable brain perfusion in critically ill neurological patients. Impaired autoregulation raises the risk of secondary brain injury. The current standard evaluation requires invasive intracranial pressure monitoring, which carries risks of infection, bleeding, and tissue damage. EIT is a non-invasive, radiation-free bedside monitoring technique that uses sc

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged ≥18 years old * Diagnosed with acute intracerebral hemorrhage, subarachnoid hemorrhage or ischemic stroke, admitted to the Neurosurgical Intensive Care Unit * Receiving routine invasive monitoring of intracranial pressure (ICP) and mean arterial pressure (MAP) * Written informed consent obtained from the legally authorized representative Exclusion Criteria: * Severe scalp damage, infection or skull defect affecting electrode placement * Craniotomy history with metal implants interfering with EIT signal acquisition Pregnancy * Terminal critical illness with estimated survival \<24 hours * Severe coagulation dysfunction or confirmed allergy to electrode materials * Unavailable for ≥2-hour continuous valid monitoring data collection
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What it tests

  • Non-invasive cerebral Electrical Impedance Tomography (EIT) monitoring
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Where

1 site
Xijing Hospital, Air Force Medical University
Xi'an, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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