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Biopsychosocial Risk Influences on the Development and Generation of Early-Onset Chronic Pain

Recruitingn/aAges 14 Years - 26 YearsAllChildren's Hospital Medical Center, Cincinnati
NCT07602595 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of the study is to discover the underlying subtypes of chronic musculoskeletal pain (muscle and joint pain) in youth. Specifically, the researchers are looking for different profiles of brain and immune system signals that affect how the body feels pain, and how these pain profiles are shaped by a person's medical history, psychology, and social environment. The goal is to develop more precise treatments for chronic pain in young people. Primary Aim: The investigators want to identify subtypes of childhood-onset chronic pain (pain lasting more than 3 months) that affects the musculoskeletal system. To do this, the study will enroll teens and young adults (ages 14-26 years) who were diagnosed with chronic pain in childhood (before the age of 18) or have a pediatric rheumatic disease or major surgery that places them at risk for developing chronic pain. The researchers will lo

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of rheumatic/autoimmune disease/pain condition or initial MSK surgery prior to age 18 * Current age 14 to 26 years * Participant (and parent/legal guardian of participants \< 18 yo) can read and write in English * At least 1 year from diagnosis of pain or rheumatic disease * For individuals with MSK surgical history, at least 1 year after initial surgical intervention * For individuals with rheumatic disease, their disease must be considered inactive Exclusion Criteria: * They have active disease (JIA or cSLE) * Other medical conditions (e.g., malignancy, acute injury, surgery, infection) that impact current health status at the time of enrollment * Currently pregnant or breastfeeding
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What it tests

  • Not applicable- observational study
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Where

1 site
Cincinnati Children's Hospital
Cincinnati, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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