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Immediate Electrophysiological Effects of Different Atrial Pacing Sites on P-Wave Characteristics

RecruitingNAAges 18 Years - anyAllShanghai Tong Ren Hospital
NCT07603648 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a prospective, single-center, non-randomized, within-subject interventional study. The purpose is to compare the immediate effects of different atrial pacing sites on atrial electrical activation, as reflected by P-wave characteristics on surface electrocardiography (ECG). During pacemaker implantation, short-term pacing will be performed sequentially at multiple predefined atrial sites, including the right atrial appendage (RAA), atrial septum, Bachmann's bundle (BB) area, and posterosuperior bundle (PSB) regions. ECG parameters will be recorded at each site to evaluate differences in P-wave duration and morphology.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Sinus rhythm at baseline * Indication for permanent pacemaker implantation with planned atrial lead placement * Willing and able to provide written informed consent Exclusion Criteria: * Long-standing persistent or permanent atrial fibrillation, or prior atrioventricular node ablation * Prior cardiac implantable electronic device (CIED) requiring revision, replacement, or upgrade * Indication for implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) * Significant valvular heart disease, cardiomyopathy, or prior cardiac surgery * Angina or acute myocardial infarction within 3 months before enrollment * Chronic use of antiarrhythmic drugs * Severe hepatic or renal dysfunction, or other serious systemic diseases * Participation in another clinical study that may interfere with the objectives of this study
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What it tests

  • Multi-site short-time pacing
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Where

2 sites
Affiliated Hospital of Zunyi Medical College
Zunyi, China
Tong Ren Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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