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The Role of CD34+ Stem Cells in the Pathogenesis of Takotsubo Syndrome

Recruitingn/aAges 18 Years - anyAllUniversity Medical Centre Ljubljana
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In plain words

What the trial is, and whether it could suit you

The underlying mechanisms of microvascular dysfunction in Takotsubo cardiomyopathy remain incompletely understood. As CD34+ cells are essential to coronary microvascular homeostasis we will investigate the potential association between CD34+ cell count and changes in left ventricular function in patients with Takotsubo cardiomyopathy at baseline and 6-month follow-up.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Minimum age 18 years * Established TTS per InterTak registry criteria * Signed consent form Exclusion Criteria: * Patients under the age of 18 years * Ischemic heart disease with at least one complete total occlusion * Other concurrent cardiomyopathies * Active infectious myocarditis * obstructive coronary artery disease * Previous hospital stay due to acute coronary syndrome (myocardial infarction) in the last 6 months before TTS acute event * Previous interventional coronary artery procedure in the last 6 months before TTS acute event * Significant valvular heart disease * Significant peripheral artery occlusive disease * Active or remitted hematologic malignancy * Patients receiving immunosuppressive therapy * Significant comorbiditeis affecting patients survival (malignancy) * Failure to obtain freely given, informed consent form.
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What it tests

  • Not listed
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Where

1 site
Advanced Heart Failure and Transplantation Program, Department of Cardiology, UMC Ljubljana, Slovenia
Ljubljana, Slovenia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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