🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effectiveness of Live Motile Sperm Sorting Device on IVF Outcomes in Advanced Paternal Age

RecruitingNAAges 40 Years - anyAllVietnam Military Medical University
NCT07605182 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Male infertility contributes significantly to infertility, particularly in advanced paternal age men where sperm DNA fragmentation is increased. Conventional density gradient centrifugation may induce oxidative stress and sperm damage. LensHooke® CA0 is a centrifugation-free sperm sorting device designed to improve sperm quality and reduce DNA fragmentation. This prospective comparative study evaluates the effectiveness of CA0 versus conventional density gradient centrifugation on post-processing sperm quality, DNA fragmentation index, blastocyst formation, euploid embryo rate, and clinical pregnancy outcomes in IVF/ICSI cycles involving men aged 40 years or older

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Male partners aged ≥ 40 years * Semen analysis: volume ≥ 1.4 mL, sperm concentration ≥ 6 million/mL, progressive motility (PR) ≥ 20% after 3-5 days of abstinence. * Female partners with ≥ 5 mature (MII) oocytes retrieved. * Couples undergoing ICSI with PGT-A and elective single embryo transfer (eSET). * Willingness to participate and sign informed consent. Exclusion Criteria: * Azoospermia, surgical sperm retrieval, or use of cryopreserved sperm. * Female uterine or ovarian conditions severely affecting IVF outcomes. * Use of donor sperm or donor oocytes
💊

What it tests

  • LensHooke® CA0 sperm sorting device
  • Density Gradient Centrifugation
📍

Where

1 site
Vietnam Military medical university
Hà Nội, Vietnam
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy