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Influence of the Gut Microbiome on Blueberry Polyphenol Metabolites

RecruitingNAAges 18 Years - anyAllColorado State University
NCT07607158 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of this study is to determine whether inter-individual differences in the gut microbiome influence exposure to blueberry polyphenol metabolites. We will use pharmacokinetics of blueberry polyphenols after an acute blueberry exposure to group individuals into "metabotypes", groups of individuals based on similarity in their metabolite profiles. We will then use multi-omic approaches to determine whether the gut microbiome predicts an individual's metabotype.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy adults ≥18 years of age * Able and willing to provide informed consent * Willing and able to adhere to all study procedures and visit requirements Exclusion Criteria: * Age \<18 years * Pregnant or breastfeeding * Presence of chronic diseases, including but not limited to cardiovascular disease, diabetes, cancer, kidney, liver, gastrointestinal, or pancreatic disease * Use of medications for chronic diseases that may interfere with study outcomes * Any condition known to negatively impact nutrient absorption (e.g., inflammatory bowel disease, celiac disease, gastroparesis) * Anemia (hemoglobin \<13.5 g/dL in men or \<12.0 g/dL in women) * Body mass index (BMI) ≤18.5 kg/m² * Use of antibiotics within the past 2 months * Recent blood draw within 1 week prior to study participation * Currently participating in another research study involving a diet or exercise intervention * Known allergy or contraindication to blueberry products or study procedures * Unwilling or unable to comply with study requirements
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What it tests

  • Freeze-dried blueberry powder beverage
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Where

1 site
Colorado State University; Food and Nutrition Clinical Research Laboratory; Gifford Building Room 216; 502 West Lake Street, Fort Collins, CO 80523
Fort Collins, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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