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โ† Trials
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Spinal Cord Associative Plasticity in Cerebral Palsy

RecruitingNAAges 18 Years - 80 YearsAllColumbia University
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In plain words

What the trial is, and whether it could suit you

Associative plasticity has been used to promote functional recovery from conditions affecting movement. The long term goal of this project is to use electrical stimulation techniques to improve arm and hand function. The goal of this prospective experimental study in adults with hemiplegic cerebral palsy (hCP) is to test the effects of pairing hand motor cortical and median nerve stimulation targeted to induce plasticity in the cervical spinal cord. Based on preliminary data in neurotypical adults, the investigators are testing the effects of this approach in adults with hCP. This study will first verify the present stimulation parameters as sufficient to promote induction of associative plasticity of sensorimotor connections for manual dexterity in adults with hCP. This will be assessed through neurophysiological, biomechanical, and clinical functional outcome measures. Successful pair

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Maintenance of caffeine and exercise levels at time of sessions * Ability to provide informed consent * Manual ability classification system (MACS) level I to III Exclusion Criteria: * History of seizures in last two years * Use of medications that lower seizure threshold * History of implanted equipment including stimulators/pacemakers
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What it tests

  • Paired brain and nerve stimulation
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Where

1 site
Columbia University Irving Medical Center
New York, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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