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Effect of Isometric Handgrip Exercise on Blood Pressure in Pregnant Women

RecruitingNAAges 18 Years - 45 YearsFemaleUniversity of Poitiers
NCT07607795 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Hypertension during pregnancy is a major public health concern, increasing the risk of cardiovascular complications for both the mother and the fetus. Women with chronic hypertension are at higher risk of adverse outcomes, and elevated blood pressure during pregnancy has also been associated with long-term cardiovascular and cognitive impairments.Regular physical activity is recognized as an effective non-pharmacological strategy to reduce blood pressure. Among different exercise modalities, isometric exercise has shown promising effects in lowering blood pressure in the general population, with minimal cardiovascular strain. However, its effects and safety in pregnant women, particularly those with hypertension, remain poorly understood.In addition to cardiovascular alterations, hypertension during pregnancy may also impact cognitive function, potentially through changes in cerebral per

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📋 Eligibility rules (as published)
Inclusion Criteria: * Pregnant women covered by the French National Health Insurance system * Pregnant women who do not object to participation in the study * Women belonging to one of the following two groups: * Women with chronic hypertension present before pregnancy (diagnosed within the past 5 years), defined as systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg, without antihypertensive treatment * Normotensive pregnant women, defined as systolic blood pressure (SBP) \< 140 mmHg and diastolic blood pressure (DBP) \< 90 mmHg before pregnancy Exclusion Criteria: * Current treatment for chronic or gestational hypertension * Known cardiovascular disease other than chronic hypertension * Age under 18 years * Persons deprived of liberty * Inability to speak or adequately understand French * Persons hospitalized without consent who are not subject to legal protection measures, and persons admitted to a health or social institution for purposes other than research * Persons currently excluded from participation in another research study * Persons under judicial protection or guardianship Type 1 or type 2 diabetes * Severe or extreme obesity (BMI ≥ 40 kg/m²) * Thyroid disease * Heavy smoking
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What it tests

  • Isometric Handgrip Exercise
  • Control Rest
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Where

1 site
Faculty of Sport Science - MOVE Laboratory - UR 20296
Poitiers, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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