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Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled Trial

RecruitingPhase 4Ages 18 Years - 65 YearsAllRawalpindi Institute of Cardiology
NCT07611890 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

After confirming eligibility, written informed consent will be obtained by a trained team member who is not involved in assigning treatment or giving the study medication. Each participant will receive a unique study number to protect privacy. Participants will be randomly assigned to receive one of the study medications using a chance-based method.The study medication will be administered through a vein before placement of the breathing tube. Blood pressure and pulse rate will be measured before the procedure and at several time points after the breathing tube is inserted.

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📋 Eligibility rules (as published)
Inclusion Criteria: American Society of Anesthesiologists (ASA) physical status III-IV. Patients who are at risk of cardiovascular events Exclusion Criteria: 1. Patients with known hypersensitivity to dexmedetomidine and Lignocaine. 2. Patients on medications that could interfere with the study (e.g., beta-blockers, calcium channel blockers). 3. Pregnant or lactating women. 4. Patients with a history of airway anomalies or difficult intubation.
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What it tests

  • IV dexmedetomidine
  • IV Lignocaine
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Where

1 site
Rawalpindi Institute of Cardiology
Rawalpindi, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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