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Effectiveness of Inspiratory Muscle Training in Weaning ICU Patients

RecruitingNAAges 18 Years - anyAllUniversity of West Attica
NCT07613021 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Patients in critical condition, due to their prolonged stay in the Intensive Care Unit (ICU), the severity of the underlying disease, and potential adverse effects of hospitalization, may develop serious complications, such as muscle atrophy and weakness, which also affect the respiratory muscles. It is characteristic that within the first 18-69 hours of mechanical ventilation (MV), proteolytic processes occur that lead to rapid atrophy of the diaphragm. Diaphragmatic dysfunction acquired during the ICU stay thus appears to have an adverse effect on weaning from mechanical ventilation, length of ICU stay, length of hospital stay, functional status, quality of life, and mortality within the ICU and the hospital. Inspiratory muscle training (IMT) has been identified as an intervention that could augment weaning, preventing the dedtrimental effects of MV. The purpose of this study is to ass

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📋 Eligibility rules (as published)
Inclusion Criteria: * ≥ 72h invasive mechanical ventilation * adequate co-operativeness as assessed by 5SQ ≥ 3. Exclusion Criteria: * terminal condition or palliative care * neuromuscular or neurological conditions prior to ICU admission
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What it tests

  • IMT
  • Early mobilization
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Where

2 sites
General Hospital
Chalcis, Greece
General Hospital "Agios Panteleimon"
Nikaia, Greece
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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