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AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing

Recruitingn/aAges 40 Years - 64 YearsFemaleGulbenkian Institute for Molecular Medicine
NCT07614542 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

AGEWISE is an observational study that aims to understand how changes in gut microbiome are related to hormonal changes during women's ageing, particularly across the different stages of menopause. The study will include healthy women aged 40 to 64 years living in Portugal, who will provide stool and blood samples and complete questionnaires about their health, lifestyle, diet, and menopausal symptoms. Researchers will study the gut microbiome together with hormone levels and markers of inflammation to better understand how menopause affects long-term health and to support the development of improved prevention strategies for women.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female sex * Aged 40 to 64 years * Resident in mainland Portugal or the islands * Able and willing to provide written informed consent * Willing to provide stool and blood samples and complete three questionnaires Exclusion Criteria: * Age below 40 years or 65 years and older * Inability to give informed consent * Refusal to provide stool or blood samples or complete questionnaires * Pregnancy * Diagnosed gastrointestinal disorders (including inflammatory bowel disease, Crohn's disease, ulcerative colitis, irritable bowel syndrome, chronic diarrhoea of unknown cause, or recurrent Clostridioides difficile infection) * Active oncological disease
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What it tests

  • Not listed
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Where

1 site
Gulbenkian Institute for Molecular Medicine, Lisbon
Lisbon, Portugal
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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