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Evaluation of a Peptide Cream on the Forearm Skin Recovery of Healthy Volunteers

RecruitingNAAges 18 Years - 50 YearsAllUniversity of Split, School of Medicine
NCT07614698 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate the efficacy of a topical peptide-based formulation containing Acetyl Hexapeptide-37 in promoting skin barrier recovery after controlled disruption in healthy adult participants. The main questions it aims to answer are: * Does the peptide cream speed up the recovery of the skin barrier after it has been slightly damaged with tape-stripping method? * How does the peptide cream compare to a placebo (a cream with no active ingredient) in improving skin hydration and reducing redness? Researchers will compare the peptide cream to a placebo to assess its effects on skin barrier recovery Participants will: * Undergo controlled disruption of the skin barrier on the volar forearm using the tape-stripping method. * One forearm will receive the peptide-based cream containing Acetyl Hexapeptide-37, while the other (contralateral) forearm will rec

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📋 Eligibility rules (as published)
Inclusion Criteria: * healthy volunteers who gave written informed consent Exclusion Criteria: * skin disease * skin damage on measurement sites * use of corticosteroids, antihistamines and immunomodulators a month prior the inclusion and during the trial * use of emollients three days prior the inclusion in the trial * non-adherence to the trial protocol * exposure to artificial and excessive natural ultraviolet (UV) radiation * pregnancy or breastfeeding * immunosuppression * allergic or irritant reactions to the constituents of the cream
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What it tests

  • Acetyl Hexapeptide-37
  • Placebo
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Where

1 site
University of Split School of Medicine
Split, Croatia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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