PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials

Inclusion Criteria: * 18 years of age or older. * Skeletally mature. * Male or female. * Undergone spinal surgery (cervical or thoracolumbar) for any indication under current medical practice. * Titania® spinal stabilization/fusion systems and/or BONEGRAFT® bone cements or BONEGRAFT® bone graft materials used during the operation. * No general health condition contraindicating surgery. * No legal restriction (military service, incarceration, or equivalent). * Provision of signed and dated Informed Consent Form (ICF) Exclusion Criteria: * Participation in another interventional clinical investigation * Suspected or confirmed pregnancy * Morbid obesity * Neurological or psychiatric conditions preventing compliance with postoperative care and instructions * Active spinal or systemic infection * High fever or leukocytosis * Severe osteoporosis and/or disease affecting bone metabolism * Known allergy or hypersensitivity to PEEK, Titanium, or PMMA * Congenital abnormality, tumor, or other condition preventing secure implant fixation or likely to shorten implant useful life * Inadequate tissue coverage at the operative site * Legally restricted individuals (military personnel, prisoners, etc.)