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Study to Evaluate the Efficacy and Safety of Deuruxolitinib in Japanese Adults With Severe Alopecia Areata

RecruitingPhase 3Ages 18 Years - 65 YearsAllSun Pharma Japan Limited
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In plain words

What the trial is, and whether it could suit you

This study evaluates the efficacy and safety of deuruxolitinib in Japanese Adults between 18 and 65 years of age who have 50% or greater scalp hair loss.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Written informed consent has been obtained. * Japanese subjects with severe alopecia areata who are between 18 and 65 years of age, inclusive, at the time of informed consent. * Definitive diagnosis of alopecia areata with a current episode of scalp hair loss lasting at least 6 months. * SALT score of 50 or more at both Screening and Baseline. Exclusion Criteria: * Treatment with systemic immunosuppressive medications or agents, including Janus kinase inhibitors, within 4 months prior to randomization. * Treatment with biologics within 6 months prior to Screening. * Positive test results for hepatitis B virus, hepatitis C virus, or human immunodeficiency virus at Screening. * History of active tuberculosis, a positive interferon gamma release assay at Screening, or evidence of tuberculosis-related lesions on chest radiography. * Clinically significant hematologic abnormalities, hepatic impairment, or renal impairment at Screening.
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What it tests

  • Deuruxolitinib
  • Placebo
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Where

18 sites
Study Site 102
Asahikawa, Japan
Study Site 117
Bunkyō City, Japan
Study Site 119
Ebina, Japan
Study Site 101
Hamamatsu, Japan
Study Site 116
Ishikawa, Japan
Study Site 112
Kitakyushu, Japan
Study Site 118
Kōtoku, Japan
Study Site 110
Kurashiki, Japan

…and 10 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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