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Machine Learning for Diagnosis of Occlusive MI in LBBB Patients

Recruitingn/aAges 18 Years - anyAllKonya City Hospital
NCT07620119 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study investigates a new way to diagnose severe heart attacks in patients who have a specific electrical heart pattern called a Left Bundle Branch Block (LBBB). When patients present to the emergency department with chest pain, doctors routinely perform an electrocardiogram (ECG) to check for a heart attack. However, the presence of an LBBB can alter the heart's electrical signals on the ECG, effectively masking or hiding the typical signs of an ongoing acute coronary occlusion (a completely blocked artery). This making it highly challenging for emergency physicians to make an accurate and rapid diagnosis. The primary purpose of this prospective and observational research is to develop and evaluate an artificial intelligence/machine learning (ML) model that can analyze digital 12-lead ECG signals to accurately predict a true blocked coronary artery in patients with LBBB. The machin

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18 years and older who present to the emergency department. Patients presenting with acute ischemic chest pain or clinical ischemia-equivalent symptoms (such as acute dyspnea, unexplained diaphoresis, or syncope). Patients with a confirmed Left Bundle Branch Block (LBBB) on their initial 12-lead electrocardiogram (ECG), which can be either newly developed or known/chronic. Patients who undergo invasive coronary angiography during their index hospital admission. Patients or their legally authorized representatives who provide written informed consent to participate in the study. Exclusion Criteria: * Patients under the age of 18. Pregnant or lactating women. Patients with poor-quality or uninterpretable digital ECG recordings due to severe artifact, missing leads, or technical errors. Patients who develop cardiopulmonary arrest before an initial diagnostic 12-lead ECG can be obtained in the emergency department. Patients transferred from another healthcare facility who have already undergone coronary angiography or revascularization. Patients who decline to participate or refuse to provide written informed consent.
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What it tests

  • Digital 12-Lead ECG Analysis and Invasive Coronary Angiography
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Where

1 site
Konya City Hospital
Konya, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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