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โ† Trials
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Opiranserin for Minimally Invasive Cholecystectomy

RecruitingNAAges 19 Years - anyAllGangnam Severance Hospital
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate whether the combination therapy of opiranserin and acetaminophen is non-inferior to the combination of non-steroidal anti-inflammatory drugs (NSAIDs) and acetaminophen for postoperative pain management after minimally invasive cholecystectomy. This is a single-center, randomized, controlled, non-inferiority clinical trial in adult patients undergoing minimally invasive cholecystectomy. Participants will be randomly assigned to either the Treatement group (opiranserin + acetaminophen) or the control group (NSAIDs + acetaminophen) in a 1:1 ratio to compare the analgesic efficacy and safety between the two analgesic regimens.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adult patient undergoing minimally invasive cholecystectomy Exclusion Criteria: * Known hypersensitivity or allergy to acetaminophen, NSAIDs, opiranserin, or fentanyl. * pre-existing chronic pain, * clinically significant ECG findings (QRS \> 200 msec, QTcF \>450 msec) * severe renal impairment * severe hepatic impairment
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What it tests

  • Opiranserin+Acetaminophen
  • Acetaminophen+NSAIDs
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Where

2 sites
Gangnam Severance Hospital
Seoul, South Korea
Gangnam Severance Hospital
Seoul, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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