💬In plain words
What the trial is, and whether it could suit you
Dental varnishes are commonly used to relieve dentin hypersensitivity by forming a protective film that occludes dentinal tubules and reduces fluid flow. This clinical investigation aims to compare the desensitizing effect of a fluoride containing varnish with a fluoride free placebo varnish. Primary and secondary objectives include evaluating short and long term reductions in dentinal hypersensitivity, assessing patient reported outcomes and daily experiences, and monitoring the varnish's tolerability and safety.
Sign in to get the eligibility rules as simple questions to take to your doctor.
📋 Eligibility rules (as published)
Inclusion Criteria:
* Informed Consent signed by the subject
* Age: 18-65 years
* Hypersensitivity assessment scale ≥ Grade 2 in
* two non-neighboring teeth in different quadrants
* The affected teeth are/have: vital, caries-free, received no restorations within the last month
* No change in medication anticipated over the next 3 months (e.g. due to upcoming surgery etc.)
Exclusion Criteria:
* Contraindications and limitations of the MD as described in the instructions for use.
* Known hypersensitivity or allergy to the device material (especially acrylates, mint flavouring)
* Pregnant or other vulnerable subjects
* Participants with severe systemic disease
* Enrolment of employees of the dental clinic of Ivoclar Vivadent AG
* Recent change in medication concerning Analgesics, NSAIDs, psychotropic drugs, other medications that may alter pain perception
* Intake of analgesics prior to appointment
* Professional desensitizing therapy in the last 3 months
* Bleaching procedures in the last 4 weeks
* Confounding dental conditions at test sites: defective or extensive restorations, abutment teeth for prostheses, recent restorations, pulpitis/periapical pathology.
* Current or recent use of desensitizing toothpastes or mouthrinses (i.e. products specifically marketed for the treatment of dentin hypersensitivity) within 4 weeks prior to enrolment
💊
What it tests
- Fluoride-containing varnish
- Fluoride-free varnish
Internal Clinic Ivoclar Vivadent AG
Schaan, Liechtenstein
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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