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Titration of Positive End-expiratory Pressure: Comparison Between Manual Thoracic or Abdominal Compression and Electrical Impedance Tomography

RecruitingNAAges 18 Years - anyAllCentre Hospitalier Saint Joseph Saint Luc de Lyon
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In plain words

What the trial is, and whether it could suit you

Patients with acute respiratory distress syndrome are placed on mechanical ventilation, and the adjustment of ventilator parameters is an important step in their care, in particular positive expiratory pressure, applied at the end of breathing. The goal of this study is to learn if continuous anterior chest compression works as well as electrical impedance tomography for positive expiratory pressure titration. Researchers will compare the two methods for each patient, in a randomly determined order : continuous anterior chest compression and electrical impedance tomography. Participants will : * have a pep titration with both techniques * be included in the study for 28 days

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Moderate to severe ARDS according to the Berlin criteria * Patient receiving sedation and continuous curarization * Free and informed consent from the patient or their loved one Exclusion Criteria: * ECMO * Pneumothorax * Chest trauma in the last 3 months * Uncontrolled shock (noradrenaline \> 5 mg/h) * Pregnant or breastfeeding woman * Protected adult within the meaning of the law * Lack of social security * Patient under AME
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What it tests

  • PEEP titrations
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Where

2 sites
GHU Henri Mondor
Créteil, France
Hôpital Saint Joseph Saint Luc
Lyon, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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