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Renal SWE as a Predictor After Pediatric Pyeloplasty for UPJO

Recruitingn/aAges 6 Months - 18 YearsAllBeni-Suef University
NCT07624019 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Ureteropelvic junction obstruction is an important cause of hydronephrosis and potentially reversible renal functional impairment in children. Although open pyeloplasty is an effective standard treatment, the degree of postoperative renal functional recovery varies between patients. This prospective observational cohort study will evaluate whether renal cortical shear wave elastography can predict renal functional recovery after open pyeloplasty in children with unilateral primary ureteropelvic junction obstruction. Renal cortical shear wave elastography will be assessed before surgery and during follow-up, and the change in elastography values will be compared with renal isotope findings after surgery. The primary objective is to evaluate the predictive value of the change in renal cortical shear wave elastography from baseline to 3 months after surgery for isotope-defined renal funct

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Children aged 6 months to 18 years. * Diagnosis of unilateral primary ureteropelvic junction obstruction. * Planned for open dismembered pyeloplasty. * Availability of preoperative renal ultrasonography, renal cortical shear wave elastography, and diuretic renography. * Written informed consent obtained from parent or legal guardian. Exclusion Criteria: * Bilateral ureteropelvic junction obstruction. * Secondary ureteropelvic junction obstruction. * Previous ipsilateral upper urinary tract surgery. * Associated major urinary tract anomalies likely to independently affect renal function, including vesicoureteral reflux, megaureter, duplex system, posterior urethral valves, or ectopic kidney. * Active urinary tract infection at the time of assessment. * Known intrinsic renal parenchymal disease unrelated to obstruction. * Inability to obtain reliable shear wave elastography measurements. * Incomplete planned follow-up.
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What it tests

  • Not listed
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Where

1 site
Department of Urology- Beni-Suef University Hospitals
Banฤซ Suwayf, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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