🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Brain Health in Transgender Adults

Recruitingn/aAges 18 Years - 45 YearsAllUniversity of Wisconsin, Madison
NCT07624747 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The purpose of this study is to test whether and how a person's brain changes in the first few months after starting gender affirming hormone therapy (GAHT). The investigators want to know if GAHT changes: 1) cerebral blood flow (CBF), 2) brain structure, connectivity, and cognitive task performance, and 3) neurocognitive function (memory, attention, executive function, processing speed). 36 male at birth and 36 female at birth participants will conduct baseline studies prior to GAHT, with a second identical set of study visits 4-6 months after GAHT begins.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * intention to undergo GAHT Exclusion Criteria: * BMI greater than 40 kg/m2 * Age greater than 45 yrs * Blood pressure greater than 140/90 (stage II hypertension) * A current diagnosis of type II diabetes * History of traumatic brain injury/concussion, stroke, or seizures * Are post-menopausal * Previously taken hormone therapy medications * Self-reported pregnancy (no pregnancy test)
💊

What it tests

  • Magnetic Resonance Imaging
  • Cognition and Health Tests
  • Optional Exercise Test
📍

Where

1 site
UW School of Medicine and Public Health
Madison, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy