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Effect of Smoking and Time of Day on Eosinophils

RecruitingNAAges 18 Years - 50 YearsAllMarek Lommatzsch
NCT07625111 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study investigates the effect of acute smoking and time of day on blood eosinophils in chronic smokers. Chronic cigarette smokers without chronic respiratory diseases smoking at least 8 cigarettes per day and never-smoking controls are examined. Blood eosinophil counts and surface molecules are measured at 8 and 12 am in both groups. In smokers, two measurements are performed (at least 4 weeks apart): one measurement with no smoking between 8 and 12 am, and another measurement with smoking of 8 cigarettes between 8 and 12 am.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Healthy current smokers * Age between 18-50 years * Smoking of at least 8 cigarettes/day Exclusion Criteria: * Chronic respiratory diseases * Any treatment with corticosteroids or other immunosuppressants * Any acute illness
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What it tests

  • Smoking for 4 hours
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Where

1 site
University of Rostock
Rostock, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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