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CST+MST Intervention on People Living With Mild-to-moderate Dementia

RecruitingNAAges 65 Years - anyAllIstituto Superiore di Sanità
NCT07625241 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Non-pharmacological interventions such as Cognitive Stimulation Therapy (CST) and physical activity are recommended for people living with mild-to-moderate dementia. Emerging evidence suggests that combining cognitive and motor interventions may provide synergistic benefits on cognition, mobility, and functional abilities. This study aims to evaluate the effectiveness of a combined CST and Motor Stimulation Treatment (MST) programme. This multicenter quasi-experimental study will involve 30 clinical centers across five Italian regions. Participants aged ≥65 years with mild-to-moderate dementia will receive 14 combined CST+MST sessions delivered twice weekly over 7 weeks. Assessments will be conducted at baseline, post-intervention, and after 14 weeks by the end of the interventions. Primary outcomes include proportion of responders on the Mini-Mental State Examination (≥2.32 points) and

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📋 Eligibility rules (as published)
Inclusion Criteria: * age ≥ 65 years; * having been assessed by a Center for Dementia and Cognitive Disorders (CCDD) who diagnosed dementia with any etiology of mild to moderate severity; * being able to perform a Timed Up and Go test (TUG) regardless of the time taken, i.e. being able to walk independently or with assistance, but without the need for human help during the test; * having no hearing or visual impairments of a degree that would preclude participation in the interventions. Exclusion Criteria: * presence of specific behavioural disorders (delusions, hallucinations, agitation, anxiety, euphoria, disinhibition, irritability, wandering) of a degree that prevents participation in the interventions; * diseases that contraindicate physical activity (e.g. severe heart failure).
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What it tests

  • Cognitive Stimulation Therapy and Motor Stimulation Treatment
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Where

1 site
Centre for Cognitive Disorders and Dementia "ASL 3 GENOVESE"
Genova, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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