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Transauricular Vagus Nerve Stimulation Frequencies for Postoperative Pain

RecruitingNAAges 18 Years - 59 YearsAllFederal University of Bahia
NCT07633444 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether different frequencies of transauricular vagus nerve stimulation (tVNS) can reduce postoperative pain and opioid consumption in adults undergoing abdominal or urologic surgery. It will also evaluate the effects of tVNS on recovery quality, autonomic function, and treatment safety. The main questions it aims to answer are: Does transauricular vagus nerve stimulation reduce postoperative opioid consumption during the first 24 hours after surgery? Do different stimulation frequencies (high-frequency and low-frequency tVNS) produce different effects on postoperative pain and autonomic responses? Is transauricular vagus nerve stimulation safe and well tolerated in surgical patients? Researchers will compare high-frequency tVNS, low-frequency tVNS, and sham stimulation (inactive stimulation) to determine their effects on postoperative pain a

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 to 59 years. * Undergoing elective abdominal or urologic surgery. * American Society of Anesthesiologists (ASA) physical status I-III. * Able and willing to provide written informed consent. Exclusion Criteria: * History of neurological disorders. * History of psychiatric disorders. * Inability to understand study procedures. * Pregnancy. * Cognitive impairment. * Communication difficulties that interfere with study assessments. * Auricular dermatitis or skin lesions at the stimulation site. * Pre-existing cardiac arrhythmia. * Chronic opioid use. * Implanted electronic medical devices, including pacemakers.
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What it tests

  • Transauricular Vagus Nerve Stimulation (tVNS)
  • Sham Transauricular Vagus Nerve Stimulation (sham tVNS)
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Where

1 site
Hospital Universitário Professor Edgard Santos, Federal University of Bahia (HUPES-UFBA)
Salvador, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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