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Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary Angiography

Recruitingn/aAges 18 Years - anyAllFundacion Investigacion Interhospitalaria Cardiov…
NCT07638137 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

AID Post-PCI Angina is as an observational, prospective, single-cohort, multicenter study designed to investigate the causes and origins of post-PCI angina by using the advance invasive diagnosis (AID) strategy combining with angiography derived physiology (ADP) in an all-comers population of patients with post-PCI angina referred for invasive coronary angiography. An all-comers population of patients with a history of previous percutaneous coronary intervention (PCI), who presented with angina or documented myocardial ischemia by non-invasive testing and are referred for invasive coronary angiography (ICA) will be enrolled. ICA will be performed with the application of the structure AID strategy to evaluate both obstructive and non-obstructive cause of myocardial ischemia. Then, angiography derived physiological assessment of epicardial coronary artery using functional coronary angiogra

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with a history of previous percutaneous coronary intervention (PCI) with drug eluting stent (DES), bare metallic stent (BMS), or drug coated balloon (DCB) due to acute coronary syndrome or chronic coronary syndrome, who presented with angina or documented myocardial ischemia by non-invasive testing and are referred for invasive coronary angiography. Exclusion Criteria: * Acute myocardial infarction (ST-segment elevation myocardial infarction \[STEMI\] and non-ST-segment elevation myocardial infarction \[NSTEMI\]). * Age \< 18 years old. * Pregnancy. * Severe left ventricle systolic dysfunction (left ventricular ejection fraction ≤30 %). * Congestive heart failure with reduced ejection fraction. * Concomitant severe valvular heart disease. * Severely decreased renal function (glomerular filtration rate \< 30 mL/min/1.73 m2). * Significant epicardial coronary artery disease unable to be treated by PCI. * Previous coronary artery bypass grafting (CABG). * Presence of any anatomic features precluding intracoronary instrumentation with pressure guidewires. * Contraindications to the administration of adenosine or acetylcholine.
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What it tests

  • An advanced invasive diagnosis (AID) strategy combining with angiography derived physiology (ADP)
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Where

5 sites
Hospital Universitario Severo Ochoa
Leganés, Spain
Hospital Clinico San Carlos
Madrid, Spain
Hospital General Universitario Gregorio Marañón
Madrid, Spain
Acalá de Henares
Madrid, Spain
Hospital Quirónsalud Valencia
Valencia, Spain
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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