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Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases

RecruitingPhase 1Ages 21 Years - 45 YearsAllAin Shams University
NCT07641933 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3. Calcium Hydroxide In retreatment cases in terms of: 1. Biological Evaluation: Biomarker (IL 1B) 2. Radiographic Evaluation: CBCT 3. Clinical Evaluation: Pain Score (VAS)

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age: 21-45 years. 2. Medically free patients. (ASA Class 1) 3. Gender: males and females 4. Patients who are cooperative at operation and in attendance at scheduled follow-up visits. 5. Restorable root canal treated permanent lower first molars with periapical lesions. 6. Small (\<5 mm) or medium periapical lesion size (5-10 mm) Exclusion Criteria: 1. Patients with a history of allergic reactions to any of the study materials. 2. Teeth that become non-restorable after complete caries excavation. 3. Teeth that have mobility or deep periodontal pockets. 4. Teeth with internal or external resorption.
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What it tests

  • Calcium Silicate Intracanal Medication
  • Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication
  • Calcium Hydroxide (Ca(OH)2) Intracanal Medication
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Where

1 site
Ain Shams University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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