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Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients

RecruitingNAAges 18 Years - anyAllUniversity of Erlangen-Nürnberg Medical School
NCT07643558 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Cancer cachexia is a common and prognostically relevant complication of advanced malignancies, characterized by systemic inflammation, increased catabolism, and reduced nutritional intake, leading to a progressive loss of skeletal muscle mass, physical performance, and quality of life. Muscle wasting negatively affects the tolerability and efficacy of oncological therapies and exacerbates distressing symptoms such as fatigue. Consequently, international guidelines recommend combined nutritional and exercise interventions as key components of supportive cancer care. However, due to treatment-related limitations, conventional exercise programs are often difficult to implement, highlighting the need for feasible, time-efficient, and individually adaptable training concepts suitable for daily life. In addition, adequate protein-rich nutrition is essential and may be supported by targeted nu

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with malignant tumors undergoing curative or palliative treatment, including breast, ovarian, esophageal, pancreatic, gastric, colon, rectal, and prostate cancer, across all UICC stages * Women and men aged 18 years or older * ECOG performance status 0-2 Exclusion Criteria: * Patients younger than 18 years * Bone metastases or skeletal involvement associated with a high risk of fracture * Pregnant or breastfeeding women * Patients with psychiatric disorders that raise concerns regarding decision-making capacity or ability to provide informed consent * Participation in other exercise and/or nutritional intervention studies within the previous 3 months * Current use of fish oil supplements * Severe cardiovascular disease, NYHA class IV
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What it tests

  • Omega 3 FA (Fish Oil)
  • Training
  • Corn Oil Placebo, 4 capsules/day for 12 weeks
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Where

1 site
Hector-Center for Nutrition, Exercise and Sports
Erlangen, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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