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โ† Trials
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Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia

RecruitingNAAges 18 Years - 65 YearsAllPulkit Grover
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In plain words

What the trial is, and whether it could suit you

The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia. The main questions it aims to answer are: Do repeated sessions of NIBS lead to a reduction in perceived pain? Do repeated sessions of NIBS lead to an improvement in quality of life? Researchers will compare different brain targets to see if effects are different between them. Participants will receive repeated daily sessions of NIBS over 4 weeks with application of pressure pain algometry, and complete various questionnaires.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Formal diagnosis of fibromyalgia made by a practicing physician * Pain resistant to common analgesics and medications for chronic pain * Existing pain for more than 3 months with an average of at least 4 on a 0 to 10 Numerical Rating Scale (NRS) * Females of child bearing potential must be at least one of the following totally abstinent from heterosexual intercourse since the last menses before start of study, or agree to concurrent use of at least two methods of birth control throughout study participation. Exclusion Criteria: * If the subject is non-ambulatory. * If the subject is female of child-bearing potential, subject must not be pregnant. * Subject must not have a history of brain surgery or uncontrolled neurological conditions, such as seizure, fainting spells, transient ischemic attack. * Subject must not have lifetime history of severe, uncontrolled mood disorders (anxiety, depression, bipolar), psychotic disorders, other neural disorders, or heart disease. * Subject must not have any implanted electronic or metallic devices. * Subject must not have heart diseases, including known arrhythmia, or severe liver or severe gastrointestinal disease or chronic severe infectious disease (e.g. HIV/AIDS).
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What it tests

  • Primary Motor Cortex Stimulation
  • Occipital Lobe Stimulation
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Where

2 sites
UPMC Pain Management
Pittsburgh, United States
Carnegie Mellon University
Pittsburgh, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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