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Breathlessness Perceptions Within Respiratory Diseases

Recruitingn/aAges 18 Years - 100 YearsAllUniversity Hospitals, Leicester
NCT07648082 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Breathlessness is a complex symptom that results in poor quality of life, increased hospitalisations and increased mortality. Breathlessness is influenced by physiological, psychological and functional factors but these are poorly explored. There are also unexplored phenomenon's such as breathing pattern. Therefore, this study aims to understand the influences of physiology, psychology, function and breathing pattern on health related quality of life in those with a respiratory disease compared to healthy controls. This project is a cross-sectional cohort study including those with a known respiratory disease and experiencing breathlessness, compared to non-breathless healthy controls. The investigators will measure your physiology through spirometry (a breathing test that tells us about their lung function), psychology through questionnaires, function through an exercise test and breath

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Aged 18 or over up to 100 * Known respiratory diagnosis\* OR Healthy control\*\* * Ongoing symptoms of breathlessness defined as ≥2 MRC dyspnoea scale * Able to communicate in English * Able to attend two study visits * Able to provide written informed consent * Known respiratory diagnosis could include, but is not limited to, COPD, Asthma, Bronchiectasis or ILD. * Healthy controls are required to have an absence of a functionally limiting condition such as respiratory, cardiovascular, or musculoskeletal. Exclusion Criteria: * • Unstable disease or undergoing investigations for unexplained symptoms * Undergone a surgery within past six weeks * Contraindications for exercise outlined by ACSM guidelines (Unstable CVD, hypertension etc) * BMI ≥ 35kg/m2 * Unable to communicate in English * Unable to provide written informed consent * Unable to abstain from smoking for 8 hours prior to testing
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What it tests

  • Not listed
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Where

1 site
Glenfield Hospital
Leicester, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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