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Association Between Circulating BDNF Levels and Atrial Cardiomyopathy in Patients Undergoing Ablation for Persistent Atrial Fibrillation

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Universitaire Dijon
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In plain words

What the trial is, and whether it could suit you

trial fibrillation (AF) is the most common cardiac arrhythmia worldwide, and its prevalence continues to rise. AF is associated with serious complications, including embolic strokes, heart failure, and mortality. Characterized by rapid, irregular, and weakened contractions of the atria, AF is considered one of the "visible" electrophysiological manifestations of a broader condition known as atrial cardiomyopathy (ACM). Disruption of normal blood flow in the atrium, particularly in the context of an endocardium predisposed to thrombosis, predisposes to thrombus formation. Once dislodged from the atrial cavity and migrating to the cerebral arteries, these thrombi can cause a cardioembolic stroke. The main risk factors for ACI/AF are metabolic syndrome and aging. CMA is a condition that is difficult to diagnose because it is not clearly defined, except through histological analysis. Guided

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Participants who have provided written consent * Patients aged 18 years or older. * Patients scheduled to undergo their first ablation procedure for persistent atrial fibrillation at the Dijon Bourgogne University Hospital Exclusion Criteria: * A person who is not enrolled in or eligible for a social security program * A person subject to a legal protective measure (guardianship, conservatorship) * Person subject to a judicial safeguard measure * Pregnant or breastfeeding woman * Adult who is legally incapacitated or unable to give consent * Ablation of paroxysmal AF with or without electroanatomical mapping
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What it tests

  • blood draw
  • CT scan
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Where

1 site
Chu Dijon Bourogne
Dijon, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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