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Gustabor Phase 2 - Treating Taste Changes During Cancer Therapy: A Randomized Study Evaluating an AI- Based Nutrition Intervention

RecruitingNAAges 18 Years - anyAllWuerzburg University Hospital
NCT07649681 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation. Although many non-pharmacological recommendations exist, it is unclear which methods are suitable for which individuals. This randomized study aims to compare the effectiveness of individualized dietary recommendations (Gustabor group) with the current standard of care -general recommendations (Control group). Participants will undergo an objective assessment of taste disorders using taste strips and questionnaires. Based on the results, the Gustabor group will receive both general and specific dietary suggestions. These will be accomapnied by AI-generated recipe suggestions tailored to specific taste disorders (e.g., more cold foods in cases of metallic taste). The control group will receive the current standard: a flye

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 * Suffering from one of the following tumor entities: Multiple myeloma, melanoma, urogenital cancer or malignant tumor of the gastrointestinal tract * Mainly oral nutrition * Subjectively perceived tumor therapy-related taste disorder * At least two clinical presentations planned within 12 weeks with a minimum interval of three weeks * Ability to participate in nutritional intervention, including use of the online portal and implementation of recipe suggestions (e.g. resources and access to a kitchen), either independently or with third-party support (e.g. by relatives, outpatient care services). Exclusion Criteria: * Pregnancy * Taste disorder explained by other causes (e.g. existing before therapy or COVID disease) * Placement in an inpatient care facility
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What it tests

  • Gustabor server
  • Standard Recommendations
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Where

6 sites
Universitätsklinikum Augsburg
Augsburg, Germany
Universitätsklinikum Erlangen
Erlangen, Germany
LMU Klinikum Krebszentrum - CCC MünchenLMU - Comprehensive Cancer Center
München, Germany
Klinikum der Technischen Universität München (TUM Klinikum)
München, Germany
Universitätsklinikum Regensburg
Regensburg, Germany
Universitätsklinikum Würzburg
Würzburg, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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