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Genetic, Microbiological and Behavioral Factors in Obesity

Recruitingn/aAges 18 Years - 65 YearsAllJan Kochanowski University
NCT07650149 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study will assess the impact of genetic markers, microbiological (microbiome) and behavioral factors on tolerance, adherence and effectiveness of dual GLP1/GIP RA in the treatment of obesity. 200 consecutive patients who meet all inclusion and none of the exclusion criteria will be enrolled.

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📋 Eligibility rules (as published)
Inclusion criteria * Age 18-65 years * Consent to participate in the study and providing informed written consent * Overweight or obese with a BMI \>27 Exclusion criteria * Contraindications to tirzepatide use: * Type 1 or type 2 diabetes * Pregnancy or breastfeeding * Cancer * Heart failure * Expected lack of patient compliance * Taking immunosuppressive medications, steroids, NSAIDs, antibiotics (within 2 weeks prior to sample collection), * Autoimmune and inflammatory diseases, acute infectious diseases, AIDS, tuberculosis * Mental illness * Alcohol dependence syndrome * Liver cirrhosis * Post-myocardial infarction or stroke
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What it tests

  • genetic polymorphism
  • gut microbiome
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Where

2 sites
Waga Zmiany
Krakow, Poland
Luxmed sp zoo
Warsaw, Poland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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