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Radiographic Cortical Thickness of the Humerus in Detecting Post-Stroke Regional Bone Loss

Recruitingn/aAges 18 Years - anyAllIstanbul Physical Medicine Rehabilitation Trainin…
NCT07651306 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Post-stroke immobilization and reduced weight-bearing frequently lead to significant regional bone mineral density loss and asymmetry, particularly in the paretic upper extremity, which increases fracture risks. While Dual-Energy X-ray Absorptiometry (DXA) is the gold standard for evaluating systemic bone loss, it primarily focuses on axial or lower extremity sites and lacks universal accessibility. Since routine shoulder radiographs offer an opportunistic screening tool to evaluate regional bone quality without additional radiation , this study aims to compare proximal humerus cortical bone thickness between the paretic and non-paretic sides in stroke patients and assess its correlation with systemic DXA values to determine its clinical utility. This cross-sectional, observational study involves a retrospective data analysis of patients aged 18 and older who experienced a single unilat

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18 years and older. * A documented history of a single unilateral stroke that occurred at least 6 months prior to evaluation. * Presence of clinical hemiparesis. * Availability of concurrent standard anteroposterior (AP) shoulder radiographs taken within 6 months post-stroke alongside systemic DXA measurements. Exclusion Criteria: * History of surgical intervention in either shoulder. History of a proximal humerus fracture. * Co-existing metabolic bone diseases, such as primary hyperparathyroidism or osteomalacia. * History of malignancy. * Documented history of corticosteroid use. * Imaging artifacts that compromise the accuracy of DXA measurements. * History of a secondary stroke.
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What it tests

  • Not listed
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Where

1 site
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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