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โ† Trials
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Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis

RecruitingNAAges 21 Years - 100 YearsAllMassachusetts Institute of Technology
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In plain words

What the trial is, and whether it could suit you

Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA. Pain, activity limitations and disability are common symptoms. Exercise is widely recommended as a non-invasive, first line strategy for people with knee OA. Yet, less than 1/3 of adults with knee OA meet recommended levels of physical activity, and rates are even lower among people who are overweight. Furthermore, adherence to evidence-based structured programs is poor once the therapeutic support is removed. End stage disease is treated by total joint replacement. Under-active people with knee OA would benefit from general walking activity, even if joint replacement surgery is expected; however, walking is difficult and motivation is low. Thus, people with knee OA encounter a difficult paradox: exercise could help de

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Any gender * 21+ years of age * Doctor-diagnosed tibiofemoral knee osteoarthritis * Self-report knee pain or stiffness on most days of the past month * Self-report of difficulty walking due to at least one knee * Self-report of restricted walking behavior (not engaging in 150 minutes of moderate walking a week) due to at least in part one knee * Able to walk one block without the use of an assistive device (e.g. a cane or walker) * Able to engage in a walking activity program with the wearable intervention for approximately 30 minutes using standing or sitting rests as needed Exclusion Criteria: * Unable to walk at least 10 minutes in the community due to an existing cardiovascular, cardiopulmonary, musculoskeletal, or neurological condition * Planning knee, hip, ankle or back surgery within the next 6-months * Ankle or hip osteoarthritis * Inflammatory arthritis (e.g., rheumatoid arthritis, psoriatic arthritis, scleroderma, Lymes Disease, Lupus) * Bilateral total knee replacements * Use of an assistive device (e.g., walker or cane) in home or in the community * Self-reported fall within the past 6-months that resulted in limitations in daily activities * Lower extremity/foot peripheral neuropathy or other sensory disorders * Diagnosed with vestibular or other balance disorder that impact walking * Open wounds or active skin irritation on the leg shank * Open wounds or active ulcers of either feet * Unstable cardiovascular disease * Unstable respiratory disease * History of past or current deep vein thrombosis * Active back pain that limits walking * Use of supplemental oxygen to walk
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What it tests

  • Dephy Exoboot
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Where

1 site
MIT Media Lab
Cambridge, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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