🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Transcutaneous Auricular Vagus Nerve Stimulation in Psoriatic Arthritis

RecruitingNAAges 18 Years - 65 YearsAllMarmara University
NCT07653009 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This prospective single-center interventional study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on disease activity, pain, quality of life, autonomic dysfunction symptoms, and inflammatory biomarkers in patients with psoriatic arthritis (PsA). Participants diagnosed with PsA according to the Classification Criteria for Psoriatic Arthritis (CASPAR) will undergo non-invasive auricular vagus nerve stimulation using the Vagustim device. Clinical outcomes including the Disease Activity Index for Psoriatic Arthritis (DAPSA), Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), pain scores, sleep quality, quality of life, anxiety/depression, and inflammatory markers including C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) will be evalu

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of psoriatic arthritis according to the CASPAR criteria * Age between 18 and 65 years * Stable treatment regimen for at least 12 weeks prior to enrollment * Visual Analog Scale (VAS) pain score ≥4 on a 0-10 scale * Moderate-to-high disease activity according to the Disease Activity Index for Psoriatic Arthritis (DAPSA) * Ability and willingness to provide written informed consent Exclusion Criteria: * Presence of an implanted cardiac device (e.g., pacemaker, implantable cardioverter-defibrillator) or implanted neurostimulator * History of epilepsy or other uncontrolled neurological disorders * Active severe infection or immunosuppressive condition (e.g., sepsis) * Pregnancy or breastfeeding * Presence of deep auricular injury, previous ear surgery, or active skin lesions involving the auricle * Inability to comply with the treatment protocol or history of severe psychiatric disorders
💊

What it tests

  • Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
📍

Where

1 site
Marmara University Pendik Training and Research Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy