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Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy

RecruitingNAAges 18 Years - 65 YearsAllTaksim Egitim ve Arastirma Hastanesi
NCT07653490 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The study will compare postoperative recovery quality, pain scores, analgesic requirements, and perioperative outcomes between patients receiving ESP block with low-flow anaesthesia and those receiving standard anaesthetic management.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18-65 years * ASA physical status I-II * Body mass index (BMI) \<35 kg/m² * Scheduled for elective laparoscopic cholecystectomy * Ability to provide written informed consent Exclusion Criteria: * Coagulopathy or bleeding disorders * Allergy to local anaesthetic agents * Infection at the block application site * Neurological or psychiatric disorders * Communication difficulties * Chronic opioid or analgesic use * Reoperation cases * Acute cholecystitis * Conversion to open surgery * Inadequate dermatomal block after ESPB * Severe intraoperative hemodynamic instability * Intraoperative blood loss ≥250 mL * Development of allergic reactions or major complications during follow-up
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What it tests

  • Erector Spinae Plane Block
  • Low Fresh Gas Flow (0.5 L/min)
  • Standard Fresh Gas Flow (3 L/min)
  • Bupivacaine
  • Sevoflurane
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Where

1 site
Taksim Training and Research Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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