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Consecutive Occupational Heat Exposure With and Without Overnight Cooling

RecruitingNAAges 50 Years - 75 YearsMaleUniversity of Ottawa
NCT07656519 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers exposed to hot environments. Current occupational heat-stress guidelines are designed to limit excessive increases in core body temperature and physiological strain during work in the heat through the use of work-rest schedules. However, these guidelines are largely based on single-day heat exposures and assume that workers recover in cool indoor environments between shifts. During heat events, many workers may instead recover in homes or accommodations that remain overheated, particularly in the absence of air conditioning. Inadequate overnight cooling may impair the body's ability to dissipate heat, increase physiological strain, and reduce tolerance to heat exposure on subsequent workdays. Older adults may be especially vulnerable due to age-related impairm

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📋 Eligibility rules (as published)
Inclusion Criteria: * Are male. * Do not smoke or have been smoke free for at least 5 years. * English or French speaking. * Ability to provide informed consent. * Are physically active (engage in exercise at least 2 times per week for ≥30 minutes) Exclusion Criteria: * Are regularly exposed to hot environments (e.g., occupational heat exposure) * Experience claustrophobia or discomfort in enclosed environments * Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness). * Serious complications related to diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy). * Uncontrolled hypertension - BP \>150 mmHg systolic or \>95 mmHg diastolic in a sitting position. * Restrictions in physical activity due to disease (e.g. intermittent claudication, renal impairment, active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis, etc.). * Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable. * Cardiac abnormalities identified during screening
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What it tests

  • Simulated occupational heat exposure with recovery at recommended indoor temperature limit
  • Simulated occupational heat exposure with recovery in an overheated indoor environment
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Where

1 site
University of Ottawa
Ottawa, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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