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Vagus Nerve Stimulation for Myelopathy

RecruitingNAAges 18 Years - anyAllWashington University School of Medicine
NCT07660250 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of this study is to generate preliminary data to establish the feasibility and effectiveness of transauricular vagus nerve stimulation (taVNS) to improve post-operative outcomes of moderate to severe degenerative cervical myelopathy (DCM)

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years of age or older * Moderate or severe degenerative cervical myelopathy according to the mJOA * Decompression surgery planned Exclusion Criteria: * • Pregnancy * Electrically active implants (e.g. pacemaker) * Known diagnosis of amyotrophic lateral sclerosis, multiple sclerosis, rheumatoid arthritis, concomitant thoracic and/or lumbar stenosis, spine tumor, HIV-related myelopathy * Ongoing cancer therapy * Ongoing use of immunomodulating or suppressive medication * Sustained bradycardia with a heartrate \<50 beats per minute for \> 5 minutes following admission. * Prior cervical spine surgery
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What it tests

  • Vagus nerve stimulation (taVNS)
  • Sham Stimulation
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Where

1 site
Washington University
St Louis, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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