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โ† Trials
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Determining Minimal Residual Disease Using ctDNA Deep Sequencing

RecruitingNAAges any - anyAllMasaryk Memorial Cancer Institute
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In plain words

What the trial is, and whether it could suit you

Preoperative neoadjuvant chemotherapy is the standard treatment for locally advanced gastrointestinal tumours. However, not all patients respond to preoperative treatment. Early identification of progression during neoadjuvant chemotherapy or diagnosis of early disease relapse during adjuvant treatment is essential to modify the treatment strategy. The aim of this project is to validate ctDNA as a biomarker of molecular relapse/progression of disease.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Consent to participate in the study * Patients with esophageal, gastric, or pancreatic cancer, stage 0-2 * Patients with locally advanced, potentially operable disease treated with systemic perioperative chemotherapy or chemoradiotherapy * Patients with metastatic disease treated with first- to third-line palliative systemic therapy Exclusion Criteria: * not specified
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What it tests

  • NGS sequencing of mutations selected based on sequencing of primary tumors
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Where

1 site
Masaryk Memorial Cancer Institute
Brno, Czechia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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